AA-Z-YVAD-FMK is a cell-permeable, irreversible pan-caspase inhibitor with anti-inflammatory and anti-tumor activities.
Cat.No
DC29098
Name
Z-YVAD-FMK
Chemical Properties
CAS
210344-97-1
Formula
C31H39N4O9F
MW
630.66116
Storage
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
References
[1]. Li H1,et al.Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release.J Immunol. 2007 Apr 15;178(8):5271-6.
[2]. Avivi-Green C, et al. Different molecular events account for butyrate-induced apoptosis in two human colon cancer cell lines.J Nutr. 2002 Jul;132(7):1812-8.
[3]. Equils O, et al. Pretreatment with pancaspase inhibitor (Z-VAD-FMK) delays but does not prevent intraperitoneal heat-killed group B Streptococcus-induced preterm delivery in a pregnant mouse model.infect Dis Obstet Gynecol. 2009;2009:749432.
[4]. Künstle G,et al. ICE-protease inhibitors block murine liver injury and apoptosis caused by CD95 or by TNF-alpha.Immunol Lett. 1997 Jan;55(1):5-10.
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