A83B4C63 Datasheet DC Chemicals

Description	A83B4C63 is a highly potent small-molecule inhibitor targeting the DNA repair enzyme polynucleotide kinase 3'-phosphatase (PNKP), exhibiting strong binding affinity with a Kd of 80 nM. Due to its limited aqueous solubility, A83B4C63 was formulated into nano-encapsulated carriers, enhancing its therapeutic potential—particularly in PTEN-deficient colorectal cancer (CRC).
Cat.No	DC70162
Name	A83B4C63

Chemical Properties

CAS	2245002-14-4
Formula	C32H28N4O6
MW	564.587927818298
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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