Abciximab (C7E3), a chimeric mouse/human monoclonal antibody fragment, is a glycoprotein (GP) IIb/IIIa inhibitor. Abciximab inhibits platelet aggregation and leucocyte adhesion by binding to the glycoprotein IIb/IIIa, vitronectin and Mac-1 receptors.
Cat.No
A1015
Name
Abciximab
Chemical Properties
CAS
143653-53-6
Synonyms
Immunoglobulin G1,anti-(human integrin aIIbb3) Fab fragment (human-mousemonoclonal c7E3 clone p7E3VHhCg1 g1-chain), disulfide withhuman-mouse monoclonal c7E3 clone p7E3VkhCk k-chain;ABCIXIMAB;Immunoglobulin G1,anti-(human integrin aIIbb3) Fab fragment (human-mousemonoclonal c7E3 clone ...;Immunoglobulin G1,anti-(human integrin aIIbb3) Fab fragment (human-mousemonoclonal c7E3 clone p7E3VHhCg1 g1-chain), disulfide;Abciximab [USAN:INN:BAN];C 7E3;CentoRx;ReoPro;Rheopro;Immunoglobulin G1, (human-mouse monoclonal c7E3 clone p7E3VHhCgamma1 Fab fragment anti-human glycoprotein IIb/IIIa receptor), disulfide with human-mouse monoclonal c7E3 clone p7E3VkappahCkappa light chain;Unii-X85G7936gv;Research Grade Abciximab(DHC33301);Reopro;Abcixifiban;c7E3 Fab
pH value
Corresponds to reference standard: PASS
Non-reduced CE-SDS
>95%
SEC-HPLC
>95%
Isoelectric Point
Corresponds to reference standard
Bacterial Endotoxins Test
Residual Proteins of Host Cell
Exogenous Residual DNA
Residual protein A
Biological Activity
Osmolality
Corresponds to reference standard: PASS
Peptide mapping
Corresponds to reference standard: PASS
N-terminal sequence
Corresponds to reference standard: PASS
References
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