Description
Abelacimab (MAA868) is a fully human IgG1 monoclonal antibody that binds with high affinity to the catalytic structural domain of FXI and locks it in the zymogen conformation, thereby preventing its activation by FXIIa or thrombin. Abelacimab can be used in thromboembolic disease studies.
Cat.No
A928
Name
Abelacimab
Chemical Properties
CAS
2098724-83-3
Synonyms
Abelacimab;Research Grade Abelacimab (DHC04202);Research Grade Abelacimab (DHC04202);Research Grade Abelacimab (DHC04202);Research Grade Abelacimab (DHC04202);Abelacimab?(anti-Factor XI);Abelacimab?(anti-Factor XI);Abelacimab?(anti-Factor XI);Abelacimab?(anti-Factor XI)
pH value
Corresponds to reference standard: PASS
Non-reduced CE-SDS
>95%
SEC-HPLC
>95%
Isoelectric Point
Corresponds to reference standard
Bacterial Endotoxins Test
Residual Proteins of Host Cell
Exogenous Residual DNA
Residual protein A
Biological Activity
Osmolality
Corresponds to reference standard: PASS
Peptide mapping
Corresponds to reference standard: PASS
N-terminal sequence
Corresponds to reference standard: PASS
References
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