ABT-751 Datasheet DC Chemicals
Description ABT-751, also known as E7010, is an orally bioavailable antimitotic sulfonamide. ABT-751 binds to the colchicine-binding site on beta-tubulin and inhibits the polymerization of microtubules, thereby preventing tumor cell replication. This agent also disrupts tumor neovascularization, reducing tumor blood flow and so inducing a cytotoxic effect.
Cat.No DC75218
Name ABT-751

Chemical Properties

CAS 141430-65-1
Formula C18H17N3O4S
MW 371.41
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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