Please store the product under the recommended conditions in the Certificate of Analysis.
Biological activity
Description
CAS NO.：175735-93-0 Product Name：alpha-conotoxin MII Synonyms：alpha-conotoxin MII;alpha-MII;MII;α-conotoxin MII;α-CTxMII EINEC: Molecular Formula：C67H103N23O22S4 Molecular Weight：1710.94
Target:
IC50: 0.5 nM (α3β2)[1].
In Vivo
In Vitro
α-Conotoxin MII (0.5-3.5 nM) blocks ACh responses in oocytes expressing α3β2 nicotinic acetylcholine receptors[1][2].
Kinase Assay
Cell Assay
Animal Administration
References
[1]. G E Cartier, et al. A New Alpha-Conotoxin Which Targets alpha3beta2 Nicotinic Acetylcholine Receptors. J Biol Chem. 1996 Mar 29;271(13):7522-8.
[2]. S C Harvey, et al. Determinants of Specificity for Alpha-Conotoxin MII on alpha3beta2 Neuronal Nicotinic Receptors. Mol Pharmacol. 1997 Feb;51(2):336-42.
[3]. J M McIntosh, et al. Conus Peptides: Novel Probes for Nicotinic Acetylcholine Receptor Structure and Function. Eur J Pharmacol. 2000 Mar 30;393(1-3):205-8.
Return Policy
If you are in any way unsatisfied with your purchase, you may return any item(s) within 365 days of its original purchase date.
Please provide your Order Number in the email. We strive to reply to all email inquiries within one business day.
