APH02174 Datasheet DC Chemicals

Description	APH02174 is a highly selective and orally active IRAK4 PROTAC degrader with the DC50 of 4.01 nM in THP-1 cells. APH02174 blocks inflammatory signals by inhibiting IL-6 release. APH02174 can be used for research on inflammatory conditions such as psoriasis vulgaris and rheumatoid arthritis.
Cat.No	DC79823
Name	APH02174

Chemical Properties

CAS	3065494-66-5
Formula	C49H55N7O8
MW	870
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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