AR Degrader-1 Datasheet DC Chemicals
Description AR Degrader-1 (Compound ML 2-9) is a monovalent molecular glue that selectively targets the androgen receptor (AR) for degradation via recruitment of the DCAF16 E3 ubiquitin ligase. Demonstrating a favorable safety profile, this compound effectively degrades AR in LNCaP prostate cancer cells without inducing significant cytotoxicity.
Cat.No DC67374
Name AR Degrader-1

Chemical Properties

CAS
Formula C24H27CLN6O4S
MW 531.03
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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