Description
Aselizumab (HuDreg-55) is an humanized IgG4 mAb against L-selectin. However, L-selectin (CD62L) is a cell adhesion molecule expressed on circulating neutrophils. It regulates migrating cells to chemotaxis towards the site of injury. Aselizumab may be account for a high rate of infections and leucopenia after truma.
Cat.No
A053
Name
Aselizumab
Chemical Properties
CAS
395639-53-9
Synonyms
Aselizumab;Aselizumab [INN]; BNP 001; HuDreg-55; Immunoglobulin G4, anti-(L-selectin) (human-mouse monoclonal HuDreg-55 heavy chain), disulfide with human-mouse monoclonal HuDreg-55 light chain, dimer;Aselizumab [inn];Bnp 001;Hudreg-55;Immunoglobulin G4, anti-(L-selectin) (human-mouse monoclonal hudreg-55 heavy chain), disulfide with human-mouse monoclonal hudreg-55 light chain, dimer;Research Grade Aselizumab (DHD03301)
pH value
Corresponds to reference standard: PASS
Non-reduced CE-SDS
>95%
SEC-HPLC
>95%
Isoelectric Point
Corresponds to reference standard
Bacterial Endotoxins Test
Residual Proteins of Host Cell
Exogenous Residual DNA
Residual protein A
Biological Activity
Osmolality
Corresponds to reference standard: PASS
Peptide mapping
Corresponds to reference standard: PASS
N-terminal sequence
Corresponds to reference standard: PASS
References
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