BBO-8520 Datasheet DC Chemicals

Description	BBO-8520 is a first-in-class, direct covalent inhibitor of both KRAS-G12C (ON) and (OFF) states. BBO-8520 displays highly significant binding to KRAS-G12C in a global cysteine proteome analysis and is 100x more selective for KRAS-G12C than for WT-KRAS and other mutant isoforms, with no measurable activity against N- or H-RAS.
Cat.No	DC60571
Name	BBO-8520

Chemical Properties

CAS
Formula
MW
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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