Description
Bexmarilimab (FP-1305) is a potent humanized anti-CLEVER-1 IgG4-antibody with an IC50 value of 4.51 nM. Bexmarilimab is capable of inducing a phenotypic M2 to M1 immune switch of tumor-associated macrophages. Bexmarilimab can be used in research of cancer.
Cat.No
A517
Name
Bexmarilimab
Chemical Properties
CAS
2259301-27-2
Synonyms
Bexmarilimab;Clevegen;FP 1305;Immunoglobulin G4 [230-proline,237-glutamic acid] [anti-(human stabilin 1)] (humanized monoclonal FP-1305 γ4-chain), disulfide with humanized monoclonal FP-1305 κ-chain, dimer;Bexmarilimab (anti-STAB1);Bexmarilimab (anti-STAB1);Bexmarilimab (anti-STAB1);Bexmarilimab (anti-STAB1);FP-1305;FP-1305;FP-1305;FP-1305
pH value
Corresponds to reference standard: PASS
Non-reduced CE-SDS
>95%
SEC-HPLC
>95%
Isoelectric Point
Corresponds to reference standard
Bacterial Endotoxins Test
Residual Proteins of Host Cell
Exogenous Residual DNA
Residual protein A
Biological Activity
Osmolality
Corresponds to reference standard: PASS
Peptide mapping
Corresponds to reference standard: PASS
N-terminal sequence
Corresponds to reference standard: PASS
References
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