BIIB021 mesylate Datasheet DC Chemicals

Description	BIIB021 (CNF2024) mesylate is the mesylate of BIIB021. BIIB021 is an orally active Hsp90 inhibitor. BIIB021 inhibits the proliferation of chronic myeloid leukemia (CML) cells, with IC50 values of K562, K562/G, 32Dp210, and 32Dp210-T315I cells are 513.99, 603.53, 110.08, and 148.07 nM, respectively. BIIB021 degrades BCR-ABL protein and inhibits the β-catenin/c-Myc pathway. BIIB021 can also induce autophagy in CML cells. BIIB021 can be used for the research of CML.
Cat.No	DC79694
Name	BIIB021 mesylate

Chemical Properties

CAS	1225041-97-3
Formula	C15H19CLN6O4S
MW	414.87
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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