BMS-345541 HCl Datasheet DC Chemicals

Description	BMS 345541 is a selective allosteric inhibitor of IKK (IC50 values are 0.3 and 4.0 μM for IKKβ and IKKα respectively). It attenuates LPS-induced cytokine production in vitro and blocks NFκB dependent transcription in mice. BMS 345541 also suppresses joint destruction in a mouse model of arthritis.
Cat.No	DC74859
Name	BMS-345541 HCl

Chemical Properties

CAS	547757-23-3
Formula	C14H18CLN5
MW	291.78
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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