BMS-986313 Datasheet DC Chemicals

Description	BMS-986313 is a potent, selective, orally active RORγt inverse agonist with EC50 of 3.6 nM in GAL-4 reporter assay in Jurkat cell line, and 50 nM in IL-17 human whole blood assay.BMS-986313 demonstrated robust efficacy in preclinical models of psoriasis (the IMQ-induced skin lesion model and the IL-23-induced acanthosis model).
Cat.No	DC70267
Name	BMS-986313

Chemical Properties

CAS	2226319-10-2
Formula	C24H23CLN4O6
MW	498.92
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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