BMS-986318 Datasheet DC Chemicals

Description	BMS-986318 is a potent nonbile acid FXR agonist with EC50s of 53 and 350 nM in the FXR Gal4 and SRC-1 recruitment assays, respectively. BMS-986318 has a suitable ADME profile, and demonstrates efficacy in the mouse bile duct ligation model of liver cholestasis and fibrosis.BMS-986318 can be used for the research of nonalcoholic steatohepatitis.
Cat.No	DC50222
Name	BMS-986318

Chemical Properties

CAS	2314378-09-9
Formula	C30H23CL2F3N4O3
MW	615.43
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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