Brentuximab Datasheet DC Chemicals

Description	Brentuximab is a monoclonal antibody targeting CD30. Brentuximab is conjugated with monomethyl auristatin E (MMAE) (HY-15162) to form the antibody-drug conjugate Brentuximab vedotin (HY-P99107), which can induce apoptosis in primary effusion lymphoma cells. Brentuximab vedotin exhibits antitumor activity with an IC50 of 10 nM against human CD30+ cancer cells.
Cat.No	A588
Name	Brentuximab

Chemical Properties

CAS	2088770-90-3
Synonyms	Brentuximab;cAC 10;Brentuximab (anti-TNFRSF8);Brentuximab (anti-TNFRSF8)
pH value	Corresponds to reference standard: PASS
Non-reduced CE-SDS	>95%
SEC-HPLC	>95%
Isoelectric Point	Corresponds to reference standard
Bacterial Endotoxins Test
Residual Proteins of Host Cell
Exogenous Residual DNA
Residual protein A
Biological Activity
Osmolality	Corresponds to reference standard: PASS
Peptide mapping	Corresponds to reference standard: PASS
N-terminal sequence	Corresponds to reference standard: PASS

References

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