BRM/BRG1 ATP Inhibitor-1 Datasheet DC Chemicals

Description	BRM/BRG1 ATP Inhibitor-1 is an orally active inhibitors of Brahma Homolog (BRM)/SMARCA2 with IC50 below 0.005 µM.
Cat.No	DC46193
Name	BRM/BRG1 ATP Inhibitor-1

Chemical Properties

CAS	2270879-17-7
Formula	C11H9F3N4O2S
MW	318.274970769882
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Papillon JPN, et al. Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers. J Med Chem. 2018 Nov 21;61(22):10155-10172

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