c-Kit-IN-3 Datasheet DC Chemicals

Description	c-Kit-IN-3 (Compound 18) is a potent and selective c-KIT kinase inhibitor with an IC50s of 4 nM, 8 nM for c-KIT wt and c-KIT T670I, respectively. c-Kit-IN-3 displays great potencies against most of the gain-offunction mutations in the juxtamembrane domain, drugresistant mutations in the ATP binding pocket, and activation loops.
Cat.No	DC66434
Name	c-Kit-IN-3

Chemical Properties

CAS	2363169-01-9
Formula	C26H20CLF3N2O4
MW	516.896216392517
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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