Golcadomide（CC-99282） Datasheet DC Chemicals
Description Golcadomide (CC-99282) is a highly potent and orally bioavailable CRBN E3 ligase modulator (CELMoD). It interacts with the CRL4 CRBN E3 ubiquitin ligase substrate receptor CRBN, facilitating the recruitment and ubiquitin-mediated proteasomal degradation of the transcription factors Ikaros and Aiolos. Golcadomide holds significant promise for research in cancer-related areas, including chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL).
Cat.No DC72103
Name Golcadomide（CC-99282）

Chemical Properties

CAS 2379572-34-4
Formula C28H30FN5O5
MW 535.57
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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