CCR2 antagonist 5 Datasheet DC Chemicals

Description	CCR2 antagonist 5 is a selective, orally active hCCR2 inhibitor with good binding affinity (IC50=37 nM) and potent functional antagonism (chemotaxis IC50=30 nM). CCR2 antagonist 5 displays a Ki of 9.6 µM for mCCR2 binding. CCR2 antagonist 5 can be used in the research of inflammatory disease.
Cat.No	DC48389
Name	CCR2 antagonist 5

Chemical Properties

CAS	1228650-83-6
Formula	C22H25F3N4O3S
MW	482.52
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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