CCR4-IN-38 Datasheet DC Chemicals
Description CCR4-IN-38 (CCR4-351) is a potent, selective, orally bioavailable CCR4 antagonist with IC50 of 50 nM (Chemotaxis inhibition).CCR4-IN-38 inhibits the recruitment of Treg into the tumor microenvironment (TME).CCR4-IN-38 elicits antitumor responses as a single agent or in combination with an immune checkpoint blockade.
Cat.No DC70292
Name CCR4-IN-38

Chemical Properties

CAS 2174938-70-4
Formula C24H27CL2N7O
MW 500.42
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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