CDK12-IN-4 Datasheet DC Chemicals

Description	CDK12-IN-4, a pyrazolotriazine, is a potent CDK12 inhibitor with an IC50 of 0.641 μM at high ATP (2 mM). CDK12-IN-4 has no effect on CDK2/Cyclin E (IC50>20 μM) and CDK9/Cyclin T1 (IC50>20 μM) at high ATP (2 mM) (WO2021116178A1).
Cat.No	DC46439
Name	CDK12-IN-4

Chemical Properties

CAS	2651196-69-7
Formula	C20H20F2N8O
MW	426.42
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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