CDK12-IN-5 Datasheet DC Chemicals

Description	CDK12-IN-5, a pyrazolotriazine, is a potent CDK12 inhibitor with an IC50 of 23.9 nM at high ATP (2 mM). CDK12-IN-5 has no effect on CDK2/Cyclin E (IC50=173 μM) and CDK9/Cyclin T1 (IC50=127 μM) at high ATP (2 mM) (WO2021116178A1).
Cat.No	DC46440
Name	CDK12-IN-5

Chemical Properties

CAS	2651200-35-8
Formula	C18H15F5N8O
MW	454.36
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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