CFT8634 Datasheet DC Chemicals

Description	CFT-8634 (CFT8634) is a potent, selective, orally bioavailable BRD9 BiDAC degrader with DC50 of 3 nM, high selectivity over BRD4 abd BRD7.Unlike BRD9 inhibition, BRD9 degradation is efficacious in preclinical models of synovial sarcoma and CFT8634 is ongoing for the treatment of SMARCB1-perturbed cancers.
Cat.No	DC70304
Name	CFT8634

Chemical Properties

CAS	2704617-93-4
Formula	C37H45F3N6O5
MW	710.785619497299
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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