CL4H6 Datasheet DC Chemicals

Description	CL4H6 is a pH-sensitive cationic lipid. CL4H6 is the main component of lipid nanoparticles (LNPs), which can be used to target and deliver siRNA, and induces a potent gene-silencing response[1][2].
Cat.No	DC57086
Name	CL4H6

Chemical Properties

CAS	2256087-35-9
Formula	C59H113NO5
MW	916.532239675522
Storage	Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

References

[1]. Amisha Sanghani, et al. Novel PEGylated Lipid Nanoparticles Have a High Encapsulation Efficiency and Effectively Deliver MRTF-B siRNA in Conjunctival Fibroblasts. Pharmaceutics. 2021 Mar 13;13(3):382. [2]. Nour Shobaki, et al. Manipulating the function of tumor-associated macrophages by siRNA-loaded lipid nanoparticles for cancer immunotherapy. J Control Release. 2020 Sep 10;325:235-248.

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