Combretastatin A-1 phosphate tetrasodium Datasheet DC Chemicals
Description Combretastatin A-1 phosphate (OXi-4503) tetrasodium, a prodrug of Combretastatin A-1, is a microtubule polymerization inhibitor that binds to the colchicine-binding site of tubulin. Combretastatin A-1 phosphate tetrasodium inhibits the Wnt/β-catenin pathway through tubulin depolymerization mediated AKT deactivation. Combretastatin A-1 phosphate tetrasodium exhibits anti-tumor and anti-vascular effects.
Cat.No DC45773
Name Combretastatin A-1 phosphate tetrasodium

Chemical Properties

CAS 288847-34-7
Formula C18H18NA4O12P2
MW 580.23
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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