CPI-169 Datasheet DC Chemicals

Description	CPI-169 is a potent inhibitor of enhancer of zeste homolog 2 (EZH2) with an IC50 value of <1nM for polycomb repressive complex 2 (PRC2). CPI-169 was shown to inhibit tumor growth in a NHL xenograft model, reducing global H3K27me3.1 It has also been shown to synergize with the B-cell lymphoma inhibitor, ABT-199, to suppress the growth of NHL cell lines. Note: CPI-169 is a racemic mixture.
Cat.No	DC75586
Name	CPI-169

Chemical Properties

CAS	1450655-76-1
Formula	C27H36N4O5S
MW	528.668
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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