ZAK-IN-2 Datasheet DC Chemicals

Description	ZAK-IN-2 (Compound 8) is a selective, covalent ZAK inhibitor with an IC50 of 11.5 nM. ZAK-IN-2 forms a covalent bond with Cys22 in the P-loop of ZAK to inhibit its kinase activity. ZAK-IN-2 inhibits the phosphorylation of the downstream target p38. ZAK-IN-2 blocks Doxorubicin-induced cleavage of Caspase 3. ZAK-IN-2 is applicable to research related to myocardial hypertrophy.
Cat.No	DC81778
Name	ZAK-IN-2

Chemical Properties

CAS	3025460-34-5
Formula	C20H27N3O2
MW	341.46
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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