PROTAC EZH2 Degrader-26 Datasheet DC Chemicals

Description	PROTAC EZH2 Degrader-26 (compound 11) is an EZH2 degrader developed based on PROTAC technology. PROTAC EZH2 Degrader-26 has an IC50 of 5.80 nM against EZH2. PROTAC EZH2 Degrader-26 exhibits micromolar-level enzyme inhibitory activity against EZH1, with an EZH1 IC50 of 0.06 μM. (Pink: Histone Methyltransferase ligand ; Blue: Cereblon ligand ; Black: ).
Cat.No	DC81360
Name	PROTAC EZH2 Degrader-26

Chemical Properties

CAS	2573307-29-4
Formula	C13H12BRN3O3
MW	338.16
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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