CUR5g Datasheet DC Chemicals

Description	CUR5g is a potent autophagy inhibitor. CUR5g selectively inhibits autophagosome degradation in cancer cells by blocking autophagosome-lysosome fusion. CUR5g blocks the recruitment of STX17 to autophagosomes via a UVRAG-dependent mechanism, resulting in the inability of autophagosomes to fuse with lysosomes. CUR5g improves the anticancer effect of Cisplatin against A549 cells both in vitro and in vivo.
Cat.No	DC72586
Name	CUR5g

Chemical Properties

CAS	1370032-20-4
Formula	C22H20N2O2
MW	344.41
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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