Cyclotraxin B Datasheet DC Chemicals
Description Cyclotraxin B, a cyclic peptide, is a highly potent and selective TrkB inhibitor without altering the binding of BDNF. Cyclotraxin B non-competitively inhibits BDNF-induced TrkB activity with an IC50  of  0.30 nM. Cyclotraxin B can crosse the blood-brain-barrier and has analgesic and anxiolytic-like behavioral effects.
Cat.No DC45284
Name Cyclotraxin B

Chemical Properties

CAS 1203586-72-4
Formula C48H73N13O17S3
MW 1200.37
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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