dBET6 Datasheet DC Chemicals
Description dBET6 is a highly potent, selective and cell-permeable degrader of BET with an IC50 of 14 nM, and has antitumor activity.
Cat.No DC12022
Name dBET6

Chemical Properties

CAS 1950634-92-0
Formula C42H45CLN8O7S
MW 841.3741
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Winter GE, et al. BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment. Mol Cell. 2017 Jul 6;67(1):5-18.e19.
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