dBRD9 dihydrochloride Datasheet DC Chemicals

Description	dBRD9 dihydrochloride is a potent and selective degrader (PROTAC) of BRD9 with IC50 of 56.6 nM in MOLM-13 cells.dBRD9 is composed of the BRD9 inhibitor BI 7273 conjugated to the cereblon E3 ligase ligand pomalidomide.dBRD9 does not degrade BRD4 or BRD7 at concentrations up to 5 uM.dBRD9 exhibits antiproliferative effects in human AML cell lines.
Cat.No	DC70339
Name	dBRD9 dihydrochloride

Chemical Properties

CAS	2341840-98-8
Formula	C40H46CLN7O10
MW	820.29
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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