Desmethyl-QCA276 Datasheet DC Chemicals
Description Desmethyl-QCA276 (PROTAC BRD4-binding moiety 4), the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM.
Cat.No DC44509
Name Desmethyl-QCA276

Chemical Properties

CAS 2126819-55-2
Formula C21H17N5OS
MW 387.46
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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