DHC-286 Datasheet DC Chemicals

Description	DHC-286 is a molecular glue degrader targeting GSPT1. DHC-286 recruits GSPT1 to the CRL4CRBN ubiquitin ligase complex, promoting GSPT1 ubiquitination and proteasomal degradation, inducing cytotoxicity. DHC-286 is promising for research of cancers such as acute myeloid leukemia.
Cat.No	DC79362
Name	DHC-286

Chemical Properties

CAS	2920443-08-7
Formula	C23H20F3N3O5
MW	475.42
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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