STING agonist-1 trihydrochloride Datasheet DC Chemicals
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Cat.No DC12321
Name STING agonist-1 trihydrochloride

Chemical Properties

CAS 2138299-34-8
Formula C42H54CL3N13O7
MW 959.32
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description
Target: STING[1].
In Vivo diABZI STING agonist-1 (trihydrochloride) activates secretion of IFNβ, IL-6, TNF, and KC/GROα (also known as CXCL1) in wild-type but not Sting−/− mice, confirming that diABZI STING agonist-1 (trihydrochloride) STING-dependent activation of type-I interferon and pro-inflammatory cytokines in vivo[1].
In Vitro
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity. Nature. 2018 Nov 7.
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