DIM1 Datasheet DC Chemicals
Description DIM1 is a sugar-alcohol-derived ionizable lipid with mannitol as the precursor. DIM1T is an optimal LNP formulation for potent mRNA delivery in adipose stem cells (ASCs). Importantly, DIM1T LNPs demonstrated considerably higher mRNA delivery efficiency than MC3, ALC-0315, and SM102. The DIM1T LNP-SEC engineered ASCs (DS-ASCs) prolong expression of hepatocyte growth factor (HGF) and C-X-C motif chemokine ligand 12 (CXCL12), which show superior wound healing efficacy over their wild-type and DIM1T LNP-mRNA counterparts in the diabetic cutaneous wound model.
Cat.No DC60543
Name DIM1

Chemical Properties

CAS
Formula
MW
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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