Disitamab vedotin Datasheet DC Chemicals
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Cat.No DC47754
Name Disitamab vedotin

Chemical Properties

CAS 2136633-23-1
Formula
MW
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：2136633-23-1
Product Name：Disitamab Vedotin
Synonyms：Disitamab Vedotin
EINEC:
Molecular Formula：
Molecular Weight：
Target: HER2
In Vivo
In Vitro The antibody part was a humanized monoclonal antibody targeting HER2, the small molecule toxin was monomethyl auristatin E (MMAE), a synthetic antineoplastic agent. A protease cleavable linker covalently attached MMAE to the antibody[2].
Kinase Assay
Cell Assay
Animal Administration

References

[1]. Deeks ED. Disitamab Vedotin: First Approval. Drugs. 2021;81(16):1929-1935. [2]. Jiang J, et al. Preclinical safety profile of disitamab vedotin：a novel anti-HER2 antibody conjugated with MMAE. Toxicol Lett. 2020;324:30-37.
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