Divarasib Datasheet DC Chemicals

Description	Divarasib (GDC-6036) is an orally bioavailable, highly potent, and selective KRAS G12C inhibitor with an IC50 of <0.01 μM. Divarasib covalently binds to the switch II (SW-II) pocket of KRAS G12C and irreversibly locks it in the inactive GDP-bound state.
Cat.No	DC58312
Name	Divarasib

Chemical Properties

CAS	2417987-45-0
Formula	C29H32CLF4N7O2
MW	622.06
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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