DprE1-IN-1 Datasheet DC Chemicals

Description	DprE1-IN-1 is a potent, orally active DprE1 inhibitor with favorable hepatocyte stability, low cytotoxicity and low hERG channel inhibition. DprE1-IN-1 displays potent activity against both drug-susceptible and clinically isolated drug-resistant Tuberculosis strains with MICs<0.1 μg/mL, as well as good intracellular antimycobacterial activity with a 1.29 log10 CFU reduction in macrophages.
Cat.No	DC49448
Name	DprE1-IN-1

Chemical Properties

CAS	920459-41-2
Formula	C19H21N3O6S2
MW	451.52
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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