EGFR mutant-IN-1 Datasheet DC Chemicals
Description EGFR mutant-IN-1, a 5-methylpyrimidopyridone derivative, is a potent and selective EGFRL858R/T790M/C797S mutant inhibitor with an IC50 of 27.5 nM, while being a significantly less potent for EGFRWT (IC50 >1.0 μM).
Cat.No DC46219
Name EGFR mutant-IN-1

Chemical Properties

CAS
Formula C34H39CLFN7O2
MW 632.17
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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