ENMD-1068 hydrochloride Datasheet DC Chemicals
Description ENMD-1068 is a novel selective PAR2 antagonist without inhibitory activity against thrombin-mediated PAR3 and PAR4 signaling; blocks TNFα production in synovial explants from patients with arthritis, and inhibits mast cell tryptase-induced recruitment of eosinophils into the pleural cavity of mice, dose dependently attenuates joint inflammation.
Cat.No DC70391
Name ENMD-1068 hydrochloride

Chemical Properties

CAS
Formula C15H29N3O2.HCL
MW 319.87
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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