Ensitrelvir fumarate Datasheet DC Chemicals
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Cat.No DC48107
Name Ensitrelvir fumarate

Chemical Properties

CAS 2757470-18-9
Formula C26H21CLF3N9O6
MW 647.95
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological activity

Description CAS NO.：2757470-18-9
Product Name：Ensitrelvir fumarate
Synonyms：Ensitrelvir fumarate
EINECS:
Molecular Formula：C26H21ClF3N9O6
Molecular Weight：647.95
Target:
In Vivo Ensitrelvir fumarate dose-dependently inhibits intrapulmonary replication of SARS-CoV-2 in mice[2].
In Vitro In a cytopathic effect (cpe)-inhibition assay of SARS-CoV-2 infected VeroE6/TMPRSS2 cells, Ensitrelvir fumarate shows the EC50 values are approximately 0.4 μM for both wild-type virus and Alpha, Beta, Gamma and Delta variants. EC50 values for SARS-CoV and MERS-CoV were 0.21 and 1.4 μM respectively[1].
Kinase Assay
Cell Assay
Animal Administration

References

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