EPZ-719 Datasheet DC Chemicals

Description	EPZ-719 is a novel and potent SETD2 inhibitor ( IC50 = 0.005 μM) with a high selectivity over other histone methyltransferases.
Cat.No	DC47616
Name	EPZ-719

Chemical Properties

CAS	2697176-16-0
Formula	C22H31FN4O3S
MW	450.57
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Lampe JW, et al. Discovery of a First-in-Class Inhibitor of the Histone Methyltransferase SETD2 Suitable for Preclinical Studies. ACS Med Chem Lett. 2021 Aug 24;12(10):1539-1545.

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