FZD7 antagonist F7H Datasheet DC Chemicals

Description	F7H is a Frizzled receptor FZD7 antagonist (IC50: 1.25 μM). Frizzled receptors (FZDs) influence Wnt signaling, mediating embryonic development and tissue homeostasis. F7H is a potent ligand for the FZD7 transmembrane domain (TMD).
Cat.No	DC65694
Name	FZD7 antagonist F7H

Chemical Properties

CAS	897109-93-2
Formula	C24H18FN3O2S2
MW	463.550
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

[1]. Li C, et al. Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7. J Med Chem. 2023 Sep 14;66(17):11855-11868.. .

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