FC-14367 Datasheet DC Chemicals

Description	FC-14367 is a PROTAC degrader targeting HIV-1 Nef protein. FC-14367 forms a ternary complex by binding Nef and Cereblon E3 ubiquitin ligase, inducing Nef ubiquitination and proteasomal degradation, restoring cell-surface CD4 and MHC-I expression and inhibiting HIV-1 replication. FC-14367 can be used in research on HIV infection and AIDS.
Cat.No	DC79598
Name	FC-14367

Chemical Properties

CAS	3066893-65-7
Formula	C38H35CLFN7O6
MW	740.18
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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