FGFR4-IN-2 Datasheet DC Chemicals
Description FGFR4-IN-2 is a potent, selective, covalent FGFR4 inhibitor with cellualr IC50 of 8.8 nM, 100-fold selectivity over FGFR2.FGFR4-IN-2 potently and selectively inhibit FGFR4 signaling through covalent modification of Cys552.FGFR4-IN-2 induces tumor regression in preclinical models of orthotopic and sorafenib-resistant HCC.
Cat.No DC70408
Name FGFR4-IN-2

Chemical Properties

CAS 1628793-01-0
Formula C23H23CL2N5O5
MW 520.367
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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