G2019S-LRRK2 inhibitor 38 Datasheet DC Chemicals

Description	G2019S-LRRK2 inhibitor 38 is a potent, selective, brain penetrant G2019S-LRRK2 kinase inhibitor with IC50 of <1 nM, cellular EC50 of 40 nM, >2,000-fold selectivity over WT LRRK2 (cellular EC50>100 uM).G2019S-LRRK2 inhibitor 38 selectively inhibit phosphorylation of Ser935 in vitro, and in brain, lung, kidney and spleen in G2019S-LRRK2 mice.
Cat.No	DC70422
Name	G2019S-LRRK2 inhibitor 38

Chemical Properties

CAS	2704564-03-2
Formula	C24H21N5
MW	379.467
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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