Galunisertib Datasheet DC Chemicals
Description Galunisertib, also known as LY2157299, is a novel, selective small molecule transforming growth factor beta receptor (TGF-βR) kinase inhibitor. LY2157299 inhibited HCC cell migration on Laminin-5, Fibronectin, Vitronectin, Fibrinogen and Collagen-I and de novo phosphorylation of pSMAD2. LY2157299 inhibited HCC migration and cell growth independently of the expression levels of TGF-βRII.
Cat.No DC75449
Name Galunisertib

Chemical Properties

CAS 700874-72-2
Formula C22H19N5O
MW 369.42
Storage 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

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