γ-AA peptide P6 (Cyclic γ-AA Peptide 6) Datasheet DC Chemicals

Description	γ-AA peptide P6 (Cyclic γ-AA P6) is a potent activator of E6 associated protein (E6AP). γ-AA peptide P6 can stimulate the self-ubiquitination of E6AP and E6AP-catalyzed substrate ubiquitination in reconstituted reactions in vitro. γ-AA peptide P6 can also enhance the ubiquitination of E6AP substrates in the cell and accelerate their degradation by the proteasome.
Cat.No	DC50317
Name	γ-AA peptide P6 (Cyclic γ-AA Peptide 6)

Chemical Properties

CAS
Formula	C73H98N10O11S
MW	1323.68
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

References

Bo Huang, et al. Activation of E6AP/UBE3A-Mediated Protein Ubiquitination and Degradation Pathways by a Cyclic γ-AA Peptide. J Med Chem. 2022 Feb 10;65(3):2497-2506.

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